Chlorex-A 12

Name: Chlorex-A 12

What is chlorpheniramine, phenylephrine, and pyrilamine?

Chlorpheniramine and pyrilamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, phenylephrine, and pyrilamine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Chlorpheniramine, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about chlorpheniramine, phenylephrine, and pyrilamine?

You should not use this medicine if you have severe coronary artery disease, diabetes, an overactive thyroid, asthma, pneumonia, or other breathing problems.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not give this medication to a child younger than 6 years old. Death can occur from the misuse of cough and cold medicines in very young children.

You should not use antihistamine medication to make a child sleepy.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dry mouth, extreme drowsiness, confusion, ringing in your ears, tremors, seizure, dilated pupils, vomiting, and loss of consciousness.

What should I avoid while taking chlorpheniramine, phenylephrine, and pyrilamine?

This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol with this medicine can cause side effects.

Ask a doctor or pharmacist before using any other cold, cough, allergy, or pain medicine. Many combination medicines contain antihistamines and decongestants. Taking certain products together can cause you to get too much of these medicines.

Avoid exposure to sunlight or tanning beds. This medicine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Usual Adult Dose for Allergic Rhinitis

Chlorpheniramine/phenylephrine/pyrilamine 2 mg-7.5 mg-12.5 mg/5 mL:
5 to 10 mL orally every 4 to 6 hours not to exceed 60 mg of phenylephrine in 24 hours.

Chlorpheniramine/phenylephrine/pyrilamine 4 mg-10 mg-25 mg oral tablet, extended release:
1 tablet orally 2 to 3 times daily.

Chlorpheniramine/phenylephrine/pyrilamine 8 mg-12.5 mg-15 mg/5 mL:
5 to 10 mL orally every 12 hours not to exceed 20 mL in 24 hours.

Chlorpheniramine/phenylephrine/pyrilamine 2 mg-10 mg-10 mg oral tablet:
1 to 2 tablets orally every 4 to 6 hours.

Usual Pediatric Dose for Cold Symptoms

Chlorpheniramine/phenylephrine/pyrilamine 2 mg-5 mg-12.5 mg/5 mL:
2 years to 6 years: 2.5 to 5 mL orally every 12 hours as needed.
6 years or older: 5 to 10 mL orally every 12 hours as needed.

Chlorpheniramine/phenylephrine/pyrilamine 2 mg-7.5 mg-12.5 mg/5 mL:
2 yrs to 5 yrs: 2.5 mL orally every 4 to 6 hours not to exceed 15 mg of phenylephrine in 24 hours.
6 yrs to 11 yrs: 5 mL orally every 4 to 6 hours not to exceed 30 mg of phenylephrine in 24 hours.
12 years or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 60 mg of phenylephrine in 24 hours.

Chlorpheniramine/phenylephrine/pyrilamine 4 mg-10 mg-25 mg oral tablet, extended release:
6 yrs to 11 yrs: 1/2 tablet orally 2 to 3 times daily.
12 years or older: 1 tablet orally 2 to 3 times daily.


Chlorpheniramine/phenylephrine/pyrilamine 8 mg-12.5 mg-15 mg/5 mL:
2 yrs to 5 yrs: 2.5 mL orally every 12 hours not to exceed 5 mL in 24 hours.
6 yrs to 12 yrs: 5 mL orally every 12 hours not to exceed 10 mL 24 hours.
12 years or older: 5 to 10 mL orally every 12 hours not to exceed 20 mL in 24 hours.

Chlorpheniramine/phenylephrine/pyrilamine 2 mg-10 mg-10 mg oral tablet:
6 yrs to 12 yrs: 1 tablet orally every 4 to 6 hours.
12 years or older: 1 to 2 tablets orally every 4 to 6 hours.

Dialysis

Data not available

Chlorpheniramine / phenylephrine / pyrilamine Pregnancy Warnings

Chlorpheniramine-phenylephrine-pyrilamine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Chlorpheniramine-phenylephrine-pyrilamine should only be given during pregnancy when benefits outweigh risks.

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