Azuphen MB

Name: Azuphen MB

Azuphen MB Interactions

Avoid taking an antacid or anti-diarrhea medicine within 1 hour before or after you take hyoscyamine, methenamine, methylene blue, phenyl salicylate, and sodium biphosphate. Antacids or anti-diarrhea medicine can make it harder for your body to absorb hyoscyamine.

If you also take ketoconazole (Nizoral), wait at least 2 hours after taking it before you take hyoscyamine, methenamine, methylene blue, phenyl salicylate, and sodium biphosphate.

Many drugs can interact with methylene blue. Tell your doctor about all other medications you use. You may need to stop using certain medicines (in some cases for up to 5 weeks before you start treatment with hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate). However, do not stop taking any of your medications without your doctor's advice. This includes:

  • any type of antidepressant;
  • diet pills, stimulants, cold or allergy medicines, ADHD medication;
  • narcotic pain medicine;
  • medication to treat Parkinson's disease or restless leg syndrome; or
  • a "triptan" migraine headache medication.

Taking any of the above medications while you are treated with medicine that contains methylene blue can cause high levels of serotonin in the body. Call your doctor right away if you have symptoms of this condition: agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, or fainting.

Many drugs can interact with this medicine. Not all possible interactions are listed here. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all your medications and any you start or stop using, especially:

  • a diuretic or "water pill";
  • medicines that change the acidity of your urine--sodium bicarbonate, potassium citrate, sodium citrate with citric acid or potassium;
  • bladder or urinary medicines--darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin; or
  • a sulfa drug.

This list is not complete and many other drugs can interact with hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

What is the most important information I should know about this medicine?

Many drugs can interact with methylene blue. During your treatment with this medicine, do not start or stop using any other medications without your doctor's advice.

If you take an antidepressant or psychiatric medication, call your doctor right away if you have signs of a serious drug interaction, including: confusion, memory problems, feeling hyperactive (mentally or physically), loss of coordination, muscle twitching, shivering, sweating, diarrhea, and/or fever.

What other drugs will affect this medicine?

Many drugs can interact with methylene blue. Tell your doctor about all other medications you use. You may need to stop using certain medicines (in some cases for up to 5 weeks before you start treatment with hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate). However, do not stop taking any of your medications without your doctor's advice. This includes:

  • any type of antidepressant;

  • diet pills, stimulants, cold or allergy medicines, ADHD medication;

  • narcotic pain medicine;

  • medication to treat Parkinson's disease or restless leg syndrome; or

  • a "triptan" migraine headache medication.

Taking any of the above medications while you are treated with medicine that contains methylene blue can cause high levels of serotonin in the body. Call your doctor right away if you have symptoms of this condition: agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, or fainting.

Many drugs can interact with this medicine. Not all possible interactions are listed here. Also, hyoscyamine can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all your medications and any you start or stop using, especially:

  • a diuretic or "water pill";

  • medicines that change the acidity of your urine--sodium bicarbonate, potassium citrate, sodium citrate with citric acid or potassium;

  • bladder or urinary medicines--darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin; or

  • a sulfa drug.

This list is not complete and many other drugs can interact with hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Uses of Azuphen MB

  • It is used to ease pain from a bladder infection.
  • It is used to treat muscle spasms of the urinary system.
  • It is used to treat urinary signs.
  • It may be given to you for other reasons. Talk with the doctor.

Overdosage

Emesis or gastric lavage. Slow intravenous administration of physostigmine in doses of 1 to 4 mg (0.5 to 1 mg in children) repeated as needed in one to two hours to reverse severe antimuscarinic symptoms.

Administration of small doses of diazepam to control excitement and seizures. Artificial respiration with oxygen if needed for respiratory depression. Adequate hydration.
Symptomatic treatment as necessary.

If overdose is suspected, contact the poison control center at 1-800-222-1222, or your local emergency room immediately

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