Alprazolam Oral

Name: Alprazolam Oral

Before Using alprazolam

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For alprazolam, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to alprazolam or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving alprazolam.

Pregnancy

Pregnancy Category Explanation
All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using alprazolam.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking alprazolam, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using alprazolam with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Delavirdine
  • Flumazenil
  • Indinavir
  • Itraconazole
  • Ketoconazole

Using alprazolam with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alfentanil
  • Amobarbital
  • Boceprevir
  • Bromazepam
  • Bromopride
  • Buprenorphine
  • Butabarbital
  • Butalbital
  • Butorphanol
  • Carbamazepine
  • Carbinoxamine
  • Carisoprodol
  • Ceritinib
  • Chloral Hydrate
  • Chlorzoxazone
  • Clarithromycin
  • Cobicistat
  • Codeine
  • Conivaptan
  • Dantrolene
  • Dasabuvir
  • Digoxin
  • Domperidone
  • Doxylamine
  • Eliglustat
  • Ethchlorvynol
  • Fentanyl
  • Flibanserin
  • Fluconazole
  • Fospropofol
  • Hydrocodone
  • Hydromorphone
  • Idelalisib
  • Levorphanol
  • Meclizine
  • Meperidine
  • Mephenesin
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methocarbamol
  • Methohexital
  • Mirtazapine
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Netupitant
  • Oxycodone
  • Oxymorphone
  • Pentobarbital
  • Periciazine
  • Phenobarbital
  • Piperaquine
  • Primidone
  • Propofol
  • Secobarbital
  • Sodium Oxybate
  • Sufentanil
  • Tapentadol
  • Thiopental
  • Tramadol
  • Voriconazole
  • Zolpidem

Using alprazolam with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amprenavir
  • Cimetidine
  • Desipramine
  • Desogestrel
  • Dienogest
  • Drospirenone
  • Erythromycin
  • Estradiol Cypionate
  • Estradiol Valerate
  • Ethinyl Estradiol
  • Ethynodiol Diacetate
  • Etonogestrel
  • Fluoxetine
  • Imipramine
  • Kava
  • Levonorgestrel
  • Mestranol
  • Mifepristone
  • Nefazodone
  • Norelgestromin
  • Norethindrone
  • Norgestimate
  • Norgestrel
  • Rifapentine
  • Roxithromycin
  • Sertraline
  • St John's Wort
  • Telaprevir
  • Theophylline
  • Troleandomycin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using alprazolam with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use alprazolam, or give you special instructions about the use of food, alcohol, or tobacco.

  • Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of alprazolam. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse, history of or
  • Depression, or history of or
  • Drug abuse or dependence, history of or
  • Lung or breathing problems (eg, respiratory depression) or
  • Mania, or history of or
  • Mental health problems, or history of or
  • Seizures, or history of—Use with caution. May make these conditions worse.
  • Glaucoma, acute narrow angle—Should not be used in patients with this condition.
  • Kidney disease or
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
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