Adasuve inhalation

Name: Adasuve inhalation

What is the most important information I should know about loxapine inhalation?

You should not use this medicine if you have breathing problems that can cause bronchospasm (such as asthma or COPD), or if you are currently having trouble breathing with cough and wheezing. You should not use loxapine if you have ever had breathing problems after using it in the past.

Loxapine inhalation can cause bronchospasm (wheezing, chest tightness, shortness of breath) that can lead to serious lung problems or make your breathing stop. This medicine must be given in a hospital or clinic setting where your doctor can quickly treat any serious side effects that occur.

Loxapine is not approved for use in psychotic conditions related to dementia. Loxapine may increase the risk of death in older adults with dementia-related conditions.

What happens if I miss a dose?

Since loxapine inhalation is used when needed, you may need only one dose. Loxapine inhalation is usually not given more than once in a 24-hour period.

Loxapine inhalation side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • a light-headed feeling, like you might pass out;

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;

  • bronchospasm (wheezing, cough, chest tightness, trouble breathing);

  • little or no urination;

  • a seizure (convulsions); or

  • severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Common side effects may include:

  • drowsiness;

  • sore throat; or

  • an unusual or unpleasant taste in the mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Precautions

Consult your pharmacist.

Before taking this medicine

You should not be treated with Adasuve if you are allergic to loxapine or amoxapine, or if you have:

  • trouble breathing with cough and wheezing;

  • a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung problems;

  • a breathing disorder you are currently treating with medication; or

  • a history of having bronchospasm after using Adasuve inhalation.

Adasuve is not approved for use in psychotic conditions related to dementia. Loxapine may increase the risk of death in older adults with dementia-related conditions.

To make sure Adasuve inhalation is safe for you, tell your doctor if you have ever had:

  • epilepsy or other seizure disorder;

  • high or low blood pressure;

  • glaucoma;

  • urination problems;

  • Parkinson's disease;

  • heart disease;

  • heart attack or stroke; or

  • if you drink alcohol or use street drugs.

Tell your doctor if you are pregnant. Using antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles.

It is not known whether loxapine inhalation passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Loxapine Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Yes Comments: -Some experts recommend that patients avoid breastfeeding for 48 hours and discard any milk produced during this interval. -An alternate drug may be preferred, especially when breastfeeding a newborn or premature infant.

This drug is present in the milk of lactating dogs. There is no information available on the use of this drug during breastfeeding.

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