Name: Aczone

How should this medicine be used?

Dapsone comes as a gel to apply to the skin. It is usually applied once (7.5% gel) or twice (5% gel) daily. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Apply dapsone exactly as directed. Do not apply more or less of it or apply it more often than prescribed by your doctor. Applying more dapsone or applying dapsone more often than recommended will not speed up or improve results, but it may irritate your skin.

It may take up to 12 weeks before you feel the full benefit of dapsone gel. If your acne does not improve after 12 weeks of treatment, call your doctor.

Be careful not to get dapsone gel in your eyes, nose, or mouth.

To use the dapsone gel, follow these steps: Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

  1. Gently wash the affected skin and pat dry with a soft towel. Ask your doctor or pharmacist to recommend a gentle cleanser.
  2. If you are using the 5% gel product, use your fingers to spread a pea-sized amount as a thin layer of gel over the affected area. If you are using the 7.5% gel product, use your fingers to spread a pea-sized amount as a thin layer of gel over the face and any other affected areas.
  3. Rub the gel in gently and completely. It may feel gritty and you may see particles in the gel.
  4. Put the cap back on the gel tube and close it tightly.
  5. Wash your hands immediately after applying the gel.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply extra gel to make up for a missed dose.

What is the most important information I should know about dapsone topical?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What happens if I overdose?

An overdose of dapsone topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Uses of Aczone

  • It is used to treat pimples (acne).

What are some things I need to know or do while I take Aczone?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Be careful if you have G6PD deficiency. Anemia may happen.
  • Use of other skin products while using Aczone may cause more irritation.
  • Using benzoyl peroxide at the same time may cause the skin or facial hair to turn yellow or orange for a short time.
  • Talk with your doctor before you use other drugs or products on your skin.
  • A blood problem called methemoglobinemia has happened with this medicine. People with this problem have had to go to the hospital. Talk with the doctor.
  • Nerve problems like loss of muscle control and muscle weakness have happened with oral dapsone. Skin reactions like toxic epidermal necrolysis have also happened with oral dapsone. These side effects have not been seen with this form of dapsone. Talk with the doctor.
  • This medicine may cause harm if swallowed. If Aczone is swallowed, call a doctor or poison control center right away.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.

How is this medicine (Aczone) best taken?

Use Aczone as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not take this medicine by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Wash your hands before and after use.
  • Clean affected part before use. Make sure to dry well.
  • Put a thin layer on the affected skin and rub in gently.

What do I do if I miss a dose?

  • Put on a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not put on 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Signs of methemoglobinemia like a blue or gray color of the lips, nails, or skin; a heartbeat that does not feel normal; seizures; very bad dizziness or passing out; very bad headache; feeling very sleepy; feeling tired or weak; or shortness of breath.
  • Back pain.
  • Dark urine or yellow skin or eyes.
  • Shortness of breath.
  • Feeling tired or weak.
  • Fever.
  • If you are planning to harm yourself or the want to harm yourself gets worse.
  • Very bad sore throat.
  • Trouble controlling body movements.
  • Belly pain.
  • Very upset stomach or throwing up.

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Aczone?

  • Store at room temperature. Do not freeze.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Important information

Contact your doctor immediately if you develop a rash while using Aczone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.