Abciximab Intravenous

Name: Abciximab Intravenous

Commonly used brand name(s)

In the U.S.

  • Reopro

Available Dosage Forms:

  • Solution

Therapeutic Class: Platelet Aggregation Inhibitor

Pharmacologic Class: Glycoprotein IIb/IIIa Inhibitor

Uses For abciximab

Abciximab is used to lessen the chance of heart attack in people who need percutaneous coronary intervention (PCI), a procedure to open blocked arteries of the heart.

A heart attack may occur when a blood vessel in the heart is blocked by a blood clot. Blood clots can sometimes form during PCI. Abciximab reduces the chance that a harmful clot will form by preventing certain cells in the blood from clumping together. Abciximab is used with aspirin and heparin, which are other medicines used to keep your blood from clotting.

abciximab is available only with your doctor's prescription.

Proper Use of abciximab

Dosing

The dose of abciximab will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of abciximab. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For prevention of blood clots during percutaneous coronary intervention (the procedure to open blocked blood vessels):
      • Adults—Initial dose: 250 micrograms (mcg) per kilogram (kg) of body weight injected 10 to 60 minutes before the procedure. Maintenance dose: 0.125 mcg per kg of body weight per minute (maximum of 10 mcg per minute) by IV for 12 hours.
      • Children—Use and dose must be determined by your doctor.
    • For patients with unstable angina that will undergo percutaneous coronary intervention within 24 hours:
      • Adults—Initial dose: 250 micrograms (mcg) per kilogram (kg) of body weight injected. Maintenance dose: 10 mcg per minute by IV for 18 to 24 hours, ending 1 hour after the procedure.
      • Children—Use and dose must be determined by your doctor.

Precautions While Using abciximab

Tell all of your medical doctors and dentists that you are using abciximab.

Check with your doctor immediately if you notice any of the following side effects:

  • Bruising or bleeding, especially bleeding that is hard to stop. Bleeding inside the body sometimes appears as bloody or black, tarry stools, or faintness.
  • Back pain; burning, pricking, tickling, or tingling sensation; leg weakness; numbness; paralysis; or problems with bowel or bladder function.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

No monograph available at this time.

Missed Dose

Consult your pharmacist.

Storage

Consult your pharmacist.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised July 2016. Copyright(c) 2016 First Databank, Inc.

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