Abacavir, lamivudine, and zidovudine

Name: Abacavir, lamivudine, and zidovudine

What should I discuss with my healthcare provider before taking Trizivir?

Do not take this medicine if you have ever had an allergic reaction to Trizivir or any medicine that contains abacavir, lamivudine, or zidovudine, including: Combivir, Epivir, Epzicom, Retrovir, or Ziagen. Once you have had an allergic reaction to abacavir, you must never use it again.

Some people taking Trizivir develop a serious condition called lactic acidosis. This may be more likely in women, in people who are overweight or have liver disease, and in people who have taken HIV/AIDS medication for a long time. Talk with your doctor about your risk.

Trizivir can also cause severe or life-threatening effects on your liver, especially if you have hepatitis B or C.

To make sure Trizivir is safe for you, tell your doctor if you have:

  • bone marrow suppression;

  • kidney disease;

  • liver disease (especially if you also use ribavirin or interferon alfa);

  • heart disease or high blood pressure; or

  • a risk factor for heart disease such as smoking, diabetes, or high cholesterol.

You may need a blood test before you start taking Trizivir for the first time, or if you are restarting the medication after stopping for reasons not related to an allergic reaction.

It is not known whether this medicine will harm an unborn baby. But HIV can be passed to your baby if you are not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. Take all of your HIV medicines as directed to control your infection.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Trizivir should not be used to treat HIV in adolescents weighing less than 90 pounds.

If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Brand Names U.S.

  • Trizivir
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